ISIS has escalated its activities greatly in Ramadan through stepping up its operations in SDF-held areas in eastern Euphrates and areas under the control of regime forces and loyalists in western Euphrates and the Syrian desert. However, ISIS sustained gross losses during the same month due to the security campaigns, attacks and clashes in different areas, according to the Syrian Observatory for Human Rights (SOHR).

According to SOHR activists, four commanders among 37 ISIS members have been killed since the beginning of Ramadan in clashes with regime forces and loyalists in the Syrian desert, security campaigns by SDF in the eastern countryside of Deir ez-Zor, clashes with SDF in Al-Tabqa city in rural Al-Raqqah, and the airstrike which targeted ex-ISIS commander in southern Afrin.

During the month of Ramadan, Syrian Observatory activists have documented 43 attacks by ISIS members and cells, from detonations, executions, surprising attacks to ambushes.